For research purposes only

Peptide Reconstitution Calculator

Work out the concentration of a reconstituted vial and the volume that contains a given quantity of compound. Enter the vial size, the volume of bacteriostatic water added, and the quantity you want to measure. All figures are laboratory measurements of concentration and volume.

Your vial

The quantity stated on the vial, in milligrams.

The volume of solvent used to reconstitute the powder.

The quantity of compound you want in a single measured volume.

All three are the U-100 scale, so one unit is 0.01 mL on any of them. The unit figure is the same whichever you pick — a smaller barrel just spreads the same volume over more of its length.

Result

Draw to 5units on a 1 mL syringe — 0.050 mL
Concentration5.00 mg/mL
Also expressed as5,000 mcg/mL
Volume to measure0.050 mL
Per unit on the syringe50.0 mcg
Equal portions per vial40
Diagram of a syringe barrel with the measured volume marked 5u

Marked position on a U-100 syringe

These figures are arithmetic only. They describe the concentration of a solution and the volume containing a stated quantity of compound. They are not instructions for use, and Apex OZ products are not supplied for human or veterinary use.

For research purposes only — not for human or veterinary use

How the calculation works

Reconstitution is the step where a lyophilised (freeze-dried) compound is returned to solution by adding a measured volume of bacteriostatic water. Two figures follow from it.

Concentration

Divide the quantity of compound in the vial by the volume of solvent added. A 10 mg vial reconstituted with 2 mL gives 5 mg per mL, or 5,000 mcg per mL.

The solvent volume changes the concentration, not the total quantity in the vial. The vial contains the same amount of compound whether you add 1 mL or 5 mL.

Volume for a stated quantity

Divide the quantity you want by the concentration. At 5 mg per mL, 250 mcg (0.25 mg) occupies 0.05 mL.

On a U-100 syringe, 1 mL is graduated into 100 units, so 0.05 mL falls at the 5 unit mark.

Common reconstitutions

Worked examples for products in the Apex OZ range, on a 1 mL U-100 syringe. Enter your own figures above for anything not listed.

VialWaterQuantityConcentrationVolumeDraw toPortions
BPC-157 10 mg2 mL250 mcg5 mg/mL0.050 mL5 units40
TB-500 10 mg2 mL500 mcg5 mg/mL0.100 mL10 units20
MOTS-c 10 mg2 mL500 mcg5 mg/mL0.100 mL10 units20
Semaglutide 5 mg2 mL250 mcg2.5 mg/mL0.100 mL10 units20
Tirzepatide 20 mg2 mL2.5 mg10 mg/mL0.250 mL25 units8
Retatrutide 10 mg2 mL1 mg5 mg/mL0.200 mL20 units10
Melanotan 2 10 mg2 mL250 mcg5 mg/mL0.050 mL5 units40
Kisspeptin-10 5 mg2 mL250 mcg2.5 mg/mL0.100 mL10 units20
Selank 10 mg2 mL500 mcg5 mg/mL0.100 mL10 units20
GHK-Cu 50 mg5 mL2 mg10 mg/mL0.200 mL20 units25

Questions

Does the volume of water change how much compound is in the vial?

No. It changes only the concentration. A larger volume of solvent produces a weaker solution spread across more millilitres; the total quantity of compound is unchanged.

Why bacteriostatic water rather than sterile water?

Bacteriostatic water contains 0.9% benzyl alcohol, which inhibits bacterial growth and allows a vial to be accessed more than once. Sterile water contains no preservative. Apex OZ supplies bacteriostatic water in 10 mL vials.

What is the difference between mg and mcg?

One milligram (mg) is 1,000 micrograms (mcg). Compound quantities in a vial are usually stated in milligrams, while smaller measured quantities are usually expressed in micrograms.

What do the numbers on an insulin syringe mean?

A U-100 syringe is graduated in units, where 100 units equal 1 mL. Each unit is therefore 0.01 mL. The units are a volume marking, not a quantity of compound — what a unit contains depends entirely on the concentration of the solution.

Does the size of the syringe change the answer?

No. A 0.3 mL, 0.5 mL and 1 mL insulin syringe are all the U-100 scale, so one unit is 0.01 mL on every one of them. The unit figure is identical — the smaller barrels simply spread the same volume over more of their length, which makes a small volume easier to read off.

Does this calculator tell me how much to use?

No. It converts between quantity, volume and concentration. Apex OZ supplies research compounds only, and no quantity is recommended or implied for use in humans or animals.

Bacteriostatic water

Supplied in 10 mL vials for laboratory reconstitution. View BAC Water.

Certificates of analysis

Independent laboratory analysis is published for tested batches, with purity, molecular weight and sample size stated against each result. View certificates.